Moro

"The trees cry out as they die, but you cannot hear them. I lie here. I listen to the pain of the forest and feel the ache of the bullet in my chest, and I dream of the day I will finally crunch that gun-woman's head in my jaws.
 * —Moro to Ashitaka"

Moro is the god of the wolves, as seen in Princess Mononoke. She is three hundred years old and possesses divine power and intelligence, as well as this, she understands and is able to speak human language.

Background
When San was just a baby, Moro caught her parents violating her forest and attacked them. San's parents then threw their baby at Moro's feet as a sacrifice and ran away. Instead of eating her, however, Moro instead raised San as her own daughter. Because of this, San acts and behaves like a wolf, and also despises humans as her mother does.