Lady Eboshi

"Watch closely everyone. I'm going to show you how to kill a god. A god of life and death.
 * —Eboshi, preparing to kill the Forest Spirit."

Lady Eboshi is the main antagonist of Princess Mononoke.She was portrayed by Yuko Tanaka in Japanese and Minnie Driver in English

In the film (spoilers).
Lady Eboshi's first scene when she with her army transportating rice to Irontown where they are attacked by San and the wolves but survive. When Ashitaka comes to Irontown he meets Eboshi  Ashitaka  learns that Eboshi is responsible for turning Nago into the demon. T hen San comes to Irontown to fight her. Later she attempts to kill the forest spirit and has her right arm bitten off by Moro, near to death she promises to rebuild a better town and leave the forest alone.

Apperence and personality.
Eboshi is a beaufitul yet stubborn, cunning woman who does whatever she wants as being the leader of Irontown. She has a black hair with pink bow and hazel eyes. She wears a kimono most of the time and speaks elgantly and seems to be fearless.